A dynamic non invasive test

Impeto Medical patented technology measures the capacity of the sweat glands to release chloride ions in response to an electrochemical stimulus. It is a dynamic test equivalent to a stress test.

A low voltage potential of variable amplitude is applied to sensors on regions of the skin with a high density of sweat glands (hands and feet) to extract chloride from the sweat and produce a current. At a low voltage, the stratum corneum acts as a capacitor and only the sweat ducts allow the transmission of ions from the skin. This ensures that measurements correspond to the local sweat function.

The technology provides a quantitative measure of chloride sweat conductance (measured in microsiemens) and its results serve as a biomarker to assess sweat gland function in relation to sweat gland innervation.