Promotional Communication. The medical devices SUDOSCAN & EZSCAN are regulated health products under the CE certification, Class IIa, according to the European Medical Device directive – SGS Belgium, notified body 1639. The test allows screening and monitoring of peripheral autonomic neuropathies. It can be performed in diabetic patients or in patients suffering from neurological diseases involving small fibers damage. As with any diagnostic test, its results must be interpreted in a global context including the clinic and other examinations performed. Please read the user manual instructions carefully. Contact our office for more information. Last update: 2021/01/12
A clinically proven test
SUDOSCAN results compared to Skin Biopsy and QSART
SUDOSCAN effectiveness have been compared to main small fiber neuropathy assessment technics in several scientific publications. G. Smith et al  have demonstrated SUDOSCAN’s diagnostic performance was comparable to Intraepidermal Nerve Fiber Density (IENFD) and QSART in detecting Neuropathy.
IENFD distal leg and foot QSART sweat volumes had similar area under the curve (AUC) to SUDOSCAN values (ESC).
IENFD: lntraepidermal Nerve Fiber Density from a skin biopsy
QSART: Quantitative Sudomotor Axon Reflex Testing- sudomotor function testing
Reference values assessed in large adult population
A large adult population have been tested for neuropathy with SUDOCAN . Thereby reference values have been determined with three levels: Electrochemical skin conductance (ESC) zones for normal sudomotor function (green), moderate sudomotor dysfunction (yellow) and severe sudomotor dysfunction (red).
 Smith G et al. The diagnostic utility of Sudoscan for distal symmetric peripheral neuropathy. Journal of Diabetes and its Complications. 2014;28(4):511-516.
 Vinik AI, Nevoret ML, Casellini C . The New Age of Sudomotor Function Testing: A Sensitive and Specific Biomarker for Diagnosis, Estimation of Severity, Monitoring Progression, and Regression in Response to Intervention. Front Endocrinol (Lausanne). 2015 Jun 11;6:94.